摘要
目的 探讨老年人院内感染铜绿假单胞菌耐药（RPA）的危险因素及预后。方法 收集我院2004～2005年老年人院内感染铜绿假单胞菌耐药共48例临床资料进行分析。结果 对48例下列因素与RPA感染有关：高龄、2种以上细菌混合感染、机械通气、患有慢性阻塞性肺疾病（COPD）、分离出RPA前15d用过氟喹诺酮及亚胺培南／美罗培南。48例中28例死亡，20例好转，病死率为58％。结论 患有慢性阻塞性肺疾病（COPD）、分离出RPA前15d用过氟喹诺酮及亚胺培南／美罗培南是RPA感染的危险因素。
Objective To study the risk factors and clinical outcomes of nosocomial infections caused by resistant psendomomas aeruginosa in elderly patients. Methods The data of 48 elderly patients of RPA nosocomial infections were analyzed between the years of 2004 and 2005 in our hospital. Results The factors associated with the development of RPA nosocomial infections were age, coinfection with other pathogens, mechanical ventilation, COPD, use of fluorquinolone and imipenem/meropenem 15 days before isolation of RPA. Of 44 cases of RPA infections,28 died, and 20 survived. Condusions Having COPD and the use of fluorquinolone and imipenem/meropenem were risk factors for RPA infection.
出处
《临床肺科杂志》
2007年第5期460-461,共2页
Journal of Clinical Pulmonary Medicine
