期刊文献+

CADASIL的影像学表现 被引量:2

Image Finding of CADASIL
暂未订购
导出
摘要 目的:研究CADASIL的影像学表现。材料与方法:报告1家系7人中4人患病,介绍了先证者的5年间颅脑CT、MRI表现。结果:颅脑MRI见脑内多发性腔梗灶和脑白质变性,颞叶前部和外囊部病变明显,且随年龄增加而加重,同时伴有脑萎缩。结论:MRI结合临床表现和家族史可诊断本病。 Purpose: To study the image findings of CADASIL. Materials and Methods: Four cases of CADASIL in one family were presented. Five years CT and MRI features of file index case was obtained. Results: Multiple lacunar infarctions and leucoaraiosis were found in the cerebral white matter and basal ganglia, especially in fire external capsule and anterior part of the temporal lobe, which progressed with the age. An atrophy of the brain was showed. Conculsion: It may be diagnosed a CADASIL if we combine the MRI findings with clinical features and family history.
出处 《现代医用影像学》 2006年第6期244-246,共3页 Modern Medical Imageology
关键词 伴有皮质下梗死和白质脑病的常染色体遗传性脑动脉病 磁共振成像 腔隙性脑梗死 白质脑病 CADASIL Magnetic resonance imaging Lacunar infarction Leuconencephalopathy
  • 相关文献

参考文献14

  • 1Singhal S,Rich P,Markus HS.The spatial distribution of MR imaging abnormalities in cerebral autosomal dominant arteriopaphy with subcortical infarcts and leukoencephalopathy and their relationship to age and clinical features AJNR.2005; 26 (10):2481-2489.
  • 2Van den Boom R,lesnick Obostein SA,van den English-Huysmans AA,et al.Cerebral autosomal dominant arteriopathy with subcortifical infarcts and leukoencephalopathy:structural MR imaging changes and apolipoprotein E genotype,AJNR,2006;29 (2):359-362.
  • 3Macri MA,Colonenese C,Garreffa G,et al.A chemical shift imaging study on reginal melabolite distubution in a CADASIL family.Magn Reson Imaging,2006; 24 (4):442-447.
  • 4Peters N,Holtmannspotter M,Opherk C,et al.Rbain volume changes in CADASIL:a serial study in pure subcortical ischemic vascular disease.Neurology,2006; 66 (10):1517-1522.
  • 5Pandey T,Abubacker S.Cerebral autosomal dominant arteriopathy with subcortifical infarcts and leukoencephalopathy:an imaging mimic of multiple sclerosis.A report of two cases.Med Princ Pract,2006; 15 (5):391-395.
  • 6张巍,吕鹤,王朝霞,牛小媛,袁云.5个CADASIL家族的核磁共振改变特点[J].中风与神经疾病杂志,2005,22(2):135-137. 被引量:15
  • 7谢晟,闫锐,肖江喜,张巍,王朝霞,袁云.2个CADASIL患者的弥散张量成像与20例正常人的比较[J].实用放射学杂志,2005,21(4):358-360. 被引量:9
  • 8刘尊敬,杨期东,刘运海,刘卫平,游咏,张岳峰,汤青平,黄青,张宁.CADASIL的临床影像和病理学特征分析(附1例报告及文献复习)[J].中风与神经疾病杂志,2005,22(4):341-343. 被引量:5
  • 9王晔,王德生.CADASIL[J].神经疾病与精神卫生,2002,2(1):60-61. 被引量:1
  • 10韩红星,张晨,李湘青.CADASIL的研究进展[J].国外医学(脑血管疾病分册),2004,12(5):387-390. 被引量:5

二级参考文献46

  • 1王朝霞,吕鹤,张英,卜定方,牛小媛,张茁,黄一宁,袁云.伴皮质下梗死和白质脑病的常染色体显性遗传性脑动脉病四个家系的NOTCH3基因突变研究[J].中华医学杂志,2004,84(14):1175-1180. 被引量:10
  • 2吕鹤,姚生,张巍,王朝霞,黄一宁,牛小媛,张茁,袁云.4个常染色体显性遗传性脑动脉病伴皮层下梗死和白质脑病(CADASIL)家族的临床表现[J].北京大学学报(医学版),2004,36(5):496-500. 被引量:16
  • 3Okeda R, Arima K, Kawai M. Arterial changes in cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) in relation to pathogenesis of diffuse myelin lossof cerebral white matter: examination of cerebral medulla
  • 4Haritunians T, Boulter J, Hicks C, et al. CADASIL Notch3 mutant proteins localize to the cell surface and bind ligand. Circ Res, 2002,90:506 - 508.
  • 5Dichgans M. Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy: phenotypic and mutational spectrum. J Neurol Sci, 2002, 203 -204:77 -80.
  • 6Dichgans M, Holtmannspotter M, Herzog J, et al. Cerebral microbleeds in CADASIL: a gradient-echo magnetic resonance imaging and autopsy study. Stroke, 2002, 33: 67 - 71.
  • 7Pfefferkorn T, yon Stuckrad-Barre S, Herzog J, et al. Reduced cerebrovascular CO2 reactivity in CADASIL: A transcranial Doppler sonography study. Stroke, 2001, 32:17 - 21.
  • 8van den Boom R, Lesnik Oberstein SA, Spilt A, et al. Cerebral hemodynamics and white matter hyperintensities in CADASIL. J Cereb Blood Flow Metab, 2003, 23: 599 - 604.
  • 9Chabriat H, Pappata S, Ostergaard L, et al. Cerebral hemodynamics in CADASIL before and after acetazolamide challenge assessed with MRI bolls tracking. Stroke, 2000, 31: 1904 - 1912.
  • 10Liebetrau M, Herzog J, Kloss CU, et al. Prolonged cerebral transit time in CADASIL: A transcranial ultrasound study. Stroke, 2002, 33:509 -512.

共引文献26

同被引文献16

  • 1谢晟,闫锐,肖江喜,张巍,王朝霞,袁云.2个CADASIL患者的弥散张量成像与20例正常人的比较[J].实用放射学杂志,2005,21(4):358-360. 被引量:9
  • 2周茂义,王滨.CADASIL的MRI特征及其病理解剖学基础[J].国外医学(临床放射学分册),2006,29(1):25-28. 被引量:3
  • 3袁云.CADASIL的诊断与鉴别诊断[J].中国神经精神疾病杂志,2007,33(11):641-643. 被引量:48
  • 4Federico A, Bianchi S, Dotti MT. The spectrum of muta- tions for CADASIL diagnosis. Neurol Sei, 2005, 26 : 117 - 124.
  • 5Van den Boom R, lesnick Obostein SA, van den English- Huysmans AA, et al. Cerebral autosomal dominant arteriop- athy with subcortifical infarcts and leukoencephalopathy: structural MR imaging changes and apolipoprotein E geno- type, AJNR, 2006, 29(2): 359-362.
  • 6Davous P. CADASIL: a review with proposed diagnostic cri- teria. Eur J Neurol, 1998, 5:219 -233.
  • 7Coulthard A, Blank SC, Bushby K, et al. Distribution of cranial MRI abnormalities in patients with symptomatic and subclinical CADASIL. Br J Radiol, 2000, 73 : 256 - 265.
  • 8van den Boom R, Lesnik Oberstein SA, van Duinen SG, et al. Subcortical lacunar lesions : an MR imaging finding in pa- tients with cerebral autosomal dominant arteriopathy with sub- cortical infarcts and leukoencephalopathy. Radiology, 2002, 224:791-796.
  • 9O' Sullivan M, Jarosz JM, Martin R J, et al. MRI hyperin- tensities of the temporal lobe and external capsule in patients with CADASIL [J]. Neurology, 2001, 56(5): 628-634.
  • 10Lassere M, McQueen F, Ostergaard M, et al. OMERACT rheumatoid arthritis magnetic resonance imaging studies. Ex- ercise 3: an international muhicenter reliability study using the RA-MRI Score, J Rheumatol, 2003, 30 (12) : 1366 - 1375.

引证文献2

二级引证文献1

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部