摘要
目的比较常用的根管冲洗剂对根管内粪肠球菌感染的清除效果。方法建立粪肠球菌根管内感染模型,实验组用4种常用的化学冲洗剂、对照组用0.9%NaCl 溶液冲洗根管。冲洗前、后计数根管内的细菌量,检测残余细菌并观察72h 细菌复苏情况。结果化学冲洗剂的杀菌效果明显好于0.9%Nacl 溶液(P<0.05),2.5%次氯酸钠及2%氯己定明显好于3% H_2O(P<0.05)。结论 2%氯己定、2%氯胺-T 的杀菌效果与2.5%次氯酸钠相似,3%H_2O 杀菌效果较弱。
Objective To compare the antimicrobial efficacy of four endodontic irrigants using an in vitro model infected by Enterococcus faecalis （Ef）. Methods The root canals of fifty extracted teeth were infected by Ef in vitro. The test groups were irrigated with 3% H20z , 2.5% sodium hypochlorite（ SH）, 2% chloramine-T（ CR）, and 2% chlorhexidine（ CHX）, respectively, and the control group was irrigated with 0. 9% NaCL The concentration of Ef in canals of each group was calculated before and after irrigation. The residual bacteria within the dentinal tubules and vitalities of the residual bacteria were also examined. Results All chemical irrigants were significantly more effective than 0.9% NaC1 （ P 〈 0.05） ; 2. 5% SH and 2% CHX were statistically more effective than 3% H2O2（P 〈0. 05）. Residual bacteria could be found in the dentinal tubules and propagated 72 h after. Conclusions 2% CR and 2% CHX had almost the equivalent antimicrobial effect as 2. 5% SH, but 3% H2O2 was less effective.
出处
《中华口腔医学杂志》
CAS
CSCD
北大核心
2007年第4期223-224,共2页
Chinese Journal of Stomatology
基金
"十五"国家科技攻关计划(2004BA720A23)
关键词
肠球菌
粪
根管冲洗剂
体外感染模型
Enterococcus faecalis
Root canal irrigants
In vitro root canal infection model
