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磷脂酶A2在小儿急性绞窄性肠梗阻早期诊断中的价值

The value of determining serum phospholipase A2 to early diagnosis of acute strangulated bowel obstruction in children
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摘要 目的 研究小儿不同程度肠梗阻与血清磷脂酶A2浓度间的关系。方法 检测不同类型、不同阶段肠梗阻患儿血清中磷脂酶A2的浓度,通过统计学分析两者之间的关系。结果急性绞窄性肠梗阻患儿血清中磷脂酶A2浓度明显高于单纯性肠梗阻组和动力性肠梗阻组(P〈0.01)。在急性绞窄性肠梗阻患儿中,肠坏死组血清中磷脂酶A2浓度明显高于肠缺血组(P〈0.01)。单纯性肠梗阻组血清中磷脂酶A2浓度与动力性肠梗阻组比较,差异无统计学意义(P〉0.05)。结论 血清磷脂酶A2对临床上早期判断是否出现急性绞窄性肠梗阻有意义,可为早期手术治疗提供参考。 Objective Comparative study on early diagnostic value of serum phospholipase A2 (PLA2) in acute strangulated bowel obstruction. Methods Serum PLA2 level were determined in different types of bowel obstruction,including strangulated obstruction,simple obstruction,torpid obstruction and contral group. Strangulated obstruction was divided into two groups:ischemia group and necrosis group.Their linear relations were statistic analyzed. Results The mean serum concentration of PLA2 in bowel obstruction group was significantly elevated comparing to those of the healthy controls (P 〈 0.01).The mean values of the strangulated obstruction group was significantly higher than those of simple obstruction and torpid obstruction group(P 〈 0.01 ). The ischemia group was significantly higher than necrosis group(P 〈 0.01 ). Conclusions The serum PLA2 level correlates closely with the severity of obstruction. It has a great value for early diagnosis of strangulated bowel obstruction and offered a solid evidence for early treatment.
出处 《中国医师进修杂志》 2007年第3期4-5,共2页 Chinese Journal of Postgraduates of Medicine
关键词 磷脂酶A2 肠梗阻 小儿 Phospholipase A2 Intestinal obstruction Children
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