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移植肾多瘤病毒相关性肾病 被引量:1

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摘要 引起人类感染的多瘤病毒有3种,即BK病毒(BKV)、JC病毒(JCV)和猿病毒-40(SV-40)。在免疫功能受损的患者中,潜伏或感染的多瘤病毒可活化而致病,导致移植肾肾病的多瘤病毒主要是BK病毒,而多瘤病毒相关性肾病(PVAN)是移植肾功能丧失的主要原因之一。随着人们对此病认识的深入、各种新型免疫抑制剂的使用和移植病理的发展,PVAN有逐年增多的趋势。2002 ~2003年,全球报道肾移植后PVAN发生率为1%~10%,PVAN导致移植肾功能丧失率为10%~80%。
作者 纪志刚 杨庆
出处 《中华器官移植杂志》 CAS CSCD 北大核心 2007年第3期192-192,共1页 Chinese Journal of Organ Transplantation
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