摘要
本实验采用家兔肠粘连模型,观察了通腑活血药对肠粘连的预防作用及肠粘连程度与血中纤维蛋白原含量的关系。结果:①通腑活血药能预防或减轻肠粘连(P＜0.05);②通腑活血药能抑制术后血中纤维蛋白原含量的增加(手术前后比P＞0.05);③术后肠粘连程度与血中纤维蛋白原含量呈正相关。表明通腑活血药预防肠粘连的机理之一是抑制术后血中纤维蛋白原的生成。
Model of intraperitoneal adhesion in rabbit was adopted. The relation of the severity of the adhesion and the content of fibrinogen in blood was oberserved as well. The result showed : ①Tong Fu herbs and blood-activating herbs could prevent or relieve adhesion. ② Such Chinese herbs could depress increment of fibrinogen content in blood after operation (the ratio before and after operation was significant. ③Adhesion severity after operation was propotional to the fibrinogen content in blood. The experiment showed that one of the mechanisms of preventing intraperitoneal adhesion by taking Tong Fu herds and blood-activating herbs was to depress the generation of fibrinogen in blood after operation. It also supplied an important experimental basis for clinically preventing and curing intraperitoneal adhesion.
出处
《中国中西医结合外科杂志》
CAS
1996年第5期358-360,共3页
Chinese Journal of Surgery of Integrated Traditional and Western Medicine
基金
国家重点工程山西铝厂技术能源处资助项目(编号J-9510)
关键词
肠粘连
通腑药
活血药
纤维蛋白原
预防
intraperitoneal adhesion, Tongfu and Blood-activating herbs, fibrinogen, prevention
