摘要
【目的】研究女性2型糖尿病患者血糖水平与骨密度的关系。【方法】以73名女性2型糖尿病患者作为研究对象,根据血糖控制情况分为血糖控制良好组32例和血糖控制不佳组41例,采用双能X线骨密度仪测定所有患者腰椎及股骨近端的骨密度,并与年龄和绝经年限相匹配的女性健康对照30例进行比较。【结果】血糖控制良好的糖尿病组和对照组各部位的骨密度值均比血糖控制不佳的糖尿病组高,差别有统计学意义(P<0.05)。血糖控制良好的糖尿病组和对照组比较,各部位的骨密度值差别无统计学意义(P>0.05)。【结论】女性2型糖尿病患者血糖水平与骨密度值呈负相关关系。
[Objective] To investigate the relationship between bone mineral density （BMD） and blood glucose level in female type 2 diabetes mellitus （T2DM） patients. [Methods] Seventy-three T2DM female patients were chosen. Among these patients, 32 had an acceptable glycemic control, 41 had poor glycemic control. The bone mineral density at lumbar spines and proximal femurs were measured with dual energy X-ray absorptiometry in all patients. The results were compared with those of the control group which contained 30 healthy females and was matched in age and year of postmenopanse. [Results] The BMD of the patients in the T2DM group with poor glycemic control was significantly lower than that in the acceptable glycemic control T2DM group and in the control group （P〈0.05）. The difference in BMD between the latter two groups was not signiticant（P 〉0.05 ）. [Conclusion] Negative correlation was found between blood glucose level and BMD.
出处
《中山大学学报（医学科学版）》
CAS
CSCD
北大核心
2007年第2期184-187,共4页
Journal of Sun Yat-Sen University:Medical Sciences
基金
广东省自然科学基金资助项目(5001707)
关键词
血糖
骨密度
糖尿病
blood glucose
bone mineral density
diabetes mellitus
