摘要
本文报告了１８０名正常人，１１８例前列腺癌和９５３例前列腺肥大病人的ＰＳＡ和ＰＡＰ测定结果。正常人、前列腺肥大和前列腺癌病人血清ＰＳＡ水平的中位数依次为１．３、３．０和１５２μｇ／ｌ、血清ＰＡＰ的中位数为０．６、１．２和１３．５μｇ／ｌ。如分别以４．２μｇ／ｌ和２．８μｇ／ｌ为正常上限，则前列腺肥大的阳性检出率为３８．９％和１８．７％。推荐血清ＰＳＡ以２０μｇ／ｌ、ＰＡＰ以１０μｇ／ｌ为鉴别前列腺癌和前列腺肥大的有效水平，此时ＰＣａ的阳性检出率分别为９７．２％和５９．２％，但ＢＰＨ的交叉率下降到５．４％和３．１％。
The Levels of Prostate specific antigen (PSA) and prostatic acid phosphatase (PAP) in 180 normal men, 118 prostatic carcinoma (PCa) and 953 benign prostatic hypertrophy(BPH) were determined. The median of PSA was 1.3μg/l in normals, 3.Oμg/l in BPH, 152μg/l in PCa and that of PAP 0. 6μg/l, 1.2μg/l and 13.5μg/l, respectively. When 4. 2μg/l of PSA and 2. 8μg/l PAP, was taken as cutoff,the positivity for BPH was 38. 8% and 18. 7%,respectively. From our study,we recommend to use a level of 20μg/l of PSA and 10μg/l of PAP to differentiate PCa from BPH,then the positivity for PCa will be 97. 2% and 59. 2%,respectively,while the false positivity in BPH will decrease to 5.4% and 3. 1%,respectively.
出处
《标记免疫分析与临床》
CAS
1996年第3期126-130,133,共6页
Labeled Immunoassays and Clinical Medicine
关键词
前列腺特异抗原
PAP
前列腺肿瘤
前列腺肥大
prostate specific antigen Acid phosphatase/prostate Prostatic neoplasms prostatic hypertrophy.
