摘要
本文对３２例不伴糖尿病的原发性高血压（ＥＨ）患者及２０名对照组进行口服葡萄糖耐量试验（ＯＧＴＴ），同时测定血糖、胰岛素、Ｃ肽、胆固醇及甘油三酯水平，结果提示ＥＨ患者存在糖耐量减低（４６．７％）、高脂血症（５０％）、肥胖（４３．８％）、高胰岛素血症（ＨＩＳ）及胰岛素抵抗（ＩＳＲ）。ＩＳＲ可能在这些代谢中起主导作用，故认为高血压病不单纯是血压升高，而是一种代谢性疾病，治疗上也不应是单纯地控制高血压，而应是防止和降低并发症的发生。
Serum glucose, insulin and C-peptide during oral glucose tolerance test (OGTT),fasting serum cholesterol and triglycerides were measured in 32 nondiabetic essential hypertensive patients and 20 normal adults. Impaired glucose tolerance (46.7%), hyperlipidemia (50%),obesity (43.8%),hyperinsulinemia and insulin resistance were observed in the hypertensive patients. Insulin resistance may play a leading role in the disease process,so it is suggested that essential hypertension is a metabolic cardiovascular syndrome and prevention or reduction of the complication should be considered in the therapy instead of mere blood pressure control.
出处
《标记免疫分析与临床》
CAS
1996年第1期8-11,19,共5页
Labeled Immunoassays and Clinical Medicine
关键词
高血压
并发症
葡萄糖耐量试验
高胰岛素血症
Hypertension Hyperinsulinism Glucose tolerance test C-Peptide Lipidemia Abnormal metabolism
