摘要
目的:研究加入银锌超细复合抗菌剂和纳米磷酸锆载银抗菌剂后硅橡胶赝复材料体外抗白色念珠菌黏附能力。方法:分别以0.5%、1%、1.5%、2%的重量比将抗菌剂加入硅橡胶赝复材料中,制成抗菌硅橡胶,用薄膜密着法测定抗菌硅橡胶对白色念珠菌的抗菌效果。结果:两种抗菌剂在0.5%重量比对白色念珠菌黏附与对照组无统计学差异,1%,1.5%,2%对白色念珠菌的抗菌性具有统计学意义。两种抗菌剂在添加量为0.5%,1%时无统计学差异,在1.5%和2%添加剂量时纳米磷酸锆载银抗菌剂抗白色念珠菌性能优于银锌超细复合抗菌剂。添加量为2%的纳米磷酸锆载银抗菌剂对白色念珠菌抗菌率>80%。结论:两种抗菌剂在添加量>1%时均有抗菌效能,在添加一定浓度时纳米磷酸锆载银抗菌剂的抗菌效能优于银锌超细复合抗菌剂。
Objictive： Study the antimicrobial effect of silicone elastomer with two different antifungal agents against candida ablbicans in vitra.Method： Antifungal agents were added into materirals respectively by 0.5%, 1%, 1.5%, 2 %W/ W agent / material ratio, then the antimicrobial effect of the silicone elastmer was examined by in vitro bacteria culture and the most probable number counting.Result：The pieces with antifungal agents showed significantly anti-fungal ability withl%, 1.5%, 2%.There were significant differences among the antifungal effect of the two agents with 1.5% and 2%.Conclusion： The impregnation of two antifungal agents with over 1% could offer silicone elastomer with strong antifungal activities against candida albicans.
出处
《临床口腔医学杂志》
2007年第2期98-99,共2页
Journal of Clinical Stomatology
关键词
抗菌剂
硅橡胶
白色念珠菌
银离子
antimicrobial agents： silicone elastomer： candida albicans： silver Ion
