摘要
目的探讨维生素A对小儿免疫功能的影响。方法选择40名2～3岁健康幼儿,随机分为观察组和对照组,分别给维生素A10000单位和安慰剂隔日口服3个月,用药前、后测定血IgA、IgG、IgM、CD4、CD8、CD4/D8,并进行统计分析。结果两组儿童用药前血IgA、IgG、IgM、CD4、CD8、CD4/D8差异统计学无意义(P>0.05),用药三个月后,观察组血IgA、IgG、IgM、CD4、CD4/D8均较对照组高,而CD8降低,差异具有显著性意义(P<0.05或<0.01),并且用药后观察组自身IgA、IgG、IgM、CD4、CD4/D8较用药前升高,CD8降低,差异具有显著性意义(P<0.01或<0.05)。结论维生素A应用后可以提高小儿免疫功能。
Objective To discuss the impact of vitamin A on the immune function of infants. Methods Forty healthy infants aged 2 - 3 years old were chosen and divided into observation group given vitamin A 1000 unit and control group given placebo for a period of 3 months. The levels of IgA, IgG, IgM, CD4, CD8, CD4/Ds in the blood of infants before and after the observation were determined. The results were statistically analyzed. Results There no significant differences were observed in the levels of IgA, IgC, IgM, CD4, CD8 ,CD4/D8 before the observation in the 2 groups （P 〉 0.05）. But the levels of IgA, IgG, IgM, CD4,CD4/D8 in the observation group were higher than that of the control group 3 months after the observation, while the CD8 was decreased, all showing significant differences （P 〈 0.05 or 〈 0.01 ）, In addition, the levels of IgA, IgG, IgM, CD4, CD4/D8 in the observation group were higher than that before the observation, while the level of CD8 was reduced also showing significant differences （P 〈 0.05 or 〈 0.01 ）. Conclusion Vitamin A can improve the immune function of infants.
出处
《中国热带医学》
CAS
2007年第4期540-541,共2页
China Tropical Medicine
基金
佛山市卫生局立项课题
关键词
维生素A
免疫功能
影响
Vitamin A
Immunity function
Effect
