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复方天麻蜜环菌片治疗椎基底动脉供血不足65例疗效观察 被引量:4

65 cases of clinical observation of applying compound armillaria mellea tablets in vertebro-basilar
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摘要 目的探讨复方天麻蜜环菌片治疗椎基底动脉供血不足(VBI)的临床疗效。方法将椎基底动脉供血不足的住院和门诊患者共130例,随机分为治疗组(65例)和对照组(65例),两组均使用复方丹参注射液为基础治疗,疗程21d;治疗组加用复方天麻蜜环菌片,疗程21d。疗程结束后,评定疗效及复查彩色多普勒超声(TCD)。结果治疗组总有效率为93.8%;对照组总有效率为81.5%,差异有统计学意义(P<0.05)。治疗组治疗前后比较,血流动力学和椎基底动脉平均血流速度等指标的变化差异均有统计学意义(P<0.05或P<0.01)。结论复方天麻蜜环菌片能降低全血黏度和血小板聚集,改善脑供血,为治疗椎基底动脉供血不足的安全有效药物。 Objective To explore the clinical effect of compound armillaria mellea tablets on the treatment of ver-tebro basilar insufficiency(VBI). Methods 130 inpatients and outpatients with vertigo caused by VBI were randomly divided into two groups. Both groups were treated with compound radix salviae miltiorrhizae injection as basic cure for 21days ,and the treatment group(65 cases) was added to orally compound armillaria mellea tablets for 21days. The curative effects were evaluated and color transcranial doppler sonography (TCD)was reporformed. Results The total effective rate of the treatment group was 93.8% ,while the that of the control group was 81.5%. The curative effect of treatment group was significant than that of the control group( P 〈0.05 ). To evaluate the effect of the treatment group before than after the treatment,the differences in targets such as cerebral blood hemocynamics and the average velocity of verbral and basilar arterias were remarkable ( P 〈 0.05 or P 〈 0.01 ). Conclusion Compound armillaria mellea tablets can reduce whole blood viscosity and anti-platelet aggregation improve brain's blood supply. So it is secure and effective to treat VBI.
出处 《中国临床保健杂志》 CAS 2007年第1期60-62,共3页 Chinese Journal of Clinical Healthcare
关键词 椎底动脉供血不足 血液流变学 中草药 Vertebrobasilar insufficiency Hemorheology Drug, chinese herbal
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  • 1[4]Watanabe N,Obuchit,Tamaim.A novel N6-substituted adenosine isolated from Armillaria mellea as a cerebral-protecting compound[J].Planta Medical,1990,56:48-52.
  • 2许艳,高佩琦,梁庆成,赵永波.黄芪多糖对脑血栓的疗效实验研究[J].中国血液流变学杂志,1999,9(3):133-136. 被引量:31

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