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脂蛋白(a)与心脑血管病的关系研究 被引量:1

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摘要 目的 探讨脂蛋白(a)[Lp(a)]水平与心脑血管疾病的关系。方法 脂蛋白(a)检测采用免疫透射比浊法,甘油三酯(TG)采用GPO-POD法,胆固醇(TC)采用胆固醇氧化酶法,低密度脂蛋白(LDL)采用酶法测定,高密度脂蛋白(HDL)采用直接一步法测定。结果 正常人群与心脑血管疾病患者的Lp(a)、TG、TC、LDL、HDL比较,t值依次为11.21,7.41,7.05和8.48,两者差异有统计学意义(P〈0.001);心脑血管疾病患者与单纯离Lp(a)患者的Lp(a)比较,t值为0.95,两者差异无统计学意义(P〉0.05);在41例心脑血管疾病患者中,其Lp(a)水平高于正常对照组的患者有9例,占心脑血管疾病患者的21.95%,显示高水平的Lp(a)与心脑血管疾病的发生、发展呈正相关。结论 LP(a)水平的增加,说明心脑血管有不同程度的损伤,显示LP(a)处于高水平,其与心脑血管疾病的发生、发展有一定的.必然联系。
出处 《国际医药卫生导报》 2007年第4期96-97,共2页 International Medicine and Health Guidance News
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