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升高高密度脂蛋白胆固醇干预的现状与展望 被引量:4

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摘要 人类经历100余年的探索,已充分认识到胆固醇特别是LDL-C在冠心病发生、发展中的重要作用。许多大规模临床研究反复证实:降低LDL-C能显著减少冠心病事件。与此同时,大量的人群研究结果也一致显示,血浆HDL-C浓度与冠心病(CHD)发病危险呈独立的负相关,低HDL-C血症是冠心病强有力的预测指标。许多证据表明HDL对动脉血管壁有直接的保护作用,并能促使动脉粥样硬化斑块消退。美国胆固醇教育计划成人治疗组第三次指南(APT Ⅲ)中,认定HDL-C〈1.0mmoL/L(40mg/d1)为异常低下,并将其作为分析个体冠心病危险性时应予考虑的一项重要危险因素。
作者 赵水平
出处 《中华心血管病杂志》 CAS CSCD 北大核心 2007年第2期190-192,共3页 Chinese Journal of Cardiology
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同被引文献41

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