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三氧化二砷联合小剂量阿糖胞苷治疗骨髓增生异常综合征的临床观察 被引量:3

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摘要 目的:观察小剂量阿糖胞苷(LD-Ara-C)和三氧化二砷(As2O3)治疗骨髓增生异常综合征(MDS)的疗效。方法:对15例MDS患者应用LD-Ara-C10~15mg/m^2,皮下注射,q12h,14~21d为一疗程,间隔14~21d重复;三氧二砷10mg/d,静脉点滴,qd,28d为一疗程。结果:基本缓解(CR)4例(26.7%),部分缓解(PR)3例(20%),无效(NR)8例(53%),总有效率为46.4%(7/15);5例(33.3%)在治疗中或达CR/PR后转为急性白血病。结论:LD-Ara-C和三氧化二砷治疗MDS有明显疗效且病人耐受性好。
出处 《实用临床医学(江西)》 CAS 2007年第1期29-29,31,共2页 Practical Clinical Medicine
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