摘要
目的:探讨氯诺昔康用于髋关节置换术后静脉镇痛的临床疗效及不良反应。方法:60例ASAⅠ-Ⅲ级全髋关节置换或半关节置换术患者随机分为两组:L组(氯诺昔康组)和M组(吗啡组),每组30例。L组采用氯诺昔康72 mg加0.9%氯化钠注射液稀释至96 mL,M组采用吗啡80 mg加0.9%氯化钠注射液稀释至96 mL。手术结束后1、2、4、8、24、48 h各时段采用视觉模拟评分(VAS)及舒适评分(BCS)评估两组镇痛效果及不良反应。结果:L组VAS、BCS与M组之间差异均无统计学意义(P均>0.05);M组头晕、恶心、呕吐、皮肤骚痒及尿潴留均高于L组(P均<0.05)。结论:氯诺昔康与吗啡用于髋关节置换术后静脉镇痛效果相当,但使用氯诺昔康静脉镇痛的不良反应较少。
Objective： To assess the analgesic effects of continuous intravenous analgesia with lornoxicam in patients with orthopedic surgery. Methods：Sixty patients undergoing orthopedic surgery were divided into two groups： group L（lornoxicam group） and group M （morphine group） with 30 in each group. The patients in group L were given lornoxicam 72 mg diluted to 96 mL with 0.9 % Sodium Chloride, background dose was 2 mL/h;The patients in group M were given morphine 80 mg diluted to 96 mL with 0.9% Sodium Chloride, background dose was 2 mL/h. Visual analogue pain scale （VAS）and Bruggman comfort score （BCS） were observed at 1,2,4,24,48 h after operation. Resuhs：VAS and BCS were no significant differences between two groups in every time after operation （P〈0.05）. The adverse events such as nausea,vomiting and urinary retention in group L were markedly lower Lhan those of group M （P〈0.05）. Conclusion. Lornoxicam used for postoperation analgesia could provide similar analgesic efficacy with morphine injection for patients undergoing orthopedic surgery, but there were little adverse events.
出处
《实用临床医学（江西）》
CAS
2007年第2期52-53,58,共3页
Practical Clinical Medicine
关键词
氯诺昔康
静脉镇痛
髋关节置换术
Iornoxicam
continuous intravenous analgesia
hip arthroplasty surgery
