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急性冠状动脉综合征与炎性相关的生化标志物研究进展

Research Progress of Biomarkers Related to Inflammation in Acute Coronary Syndrome
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摘要 局部或全身性炎症在急性冠状动脉综合征(ACS)中起着重要作用。骨髓过氧化物酶(MPO)、基质金属蛋白酶-9(MMP-9)、可溶性CD40配体(sCD40L)、B型利钠肽(BNP)和白细胞介素-6(IL-6)等参与这种炎性反应过程及其调节,作为ACS的炎症标志物,与不稳定粥样斑块破裂密切相关,可作为动脉粥样硬化斑块不稳定的标志。 Local or general inflammation plays a great role in Acute Coronary Syndrome(ACS). Myoloperoxidase(MPO), matrix metalloproteinase-9 ( MMP-9 ), soluble CD40 L( sCD40 L), B-typo natriurefic peptide(BNP), Interleukin-6 (IL-6) are involved in inflammatory reaction and its regualafion. AS the markers of the inflammation, all of these have tightly relationship with the rupture of the unstable atheromatous plagues and may serve as a potential marker of unstable plague.
作者 余强 马根山
出处 《医学综述》 2007年第5期389-392,共4页 Medical Recapitulate
基金 江苏省卫生厅资助项目(wk0510)
关键词 急性冠状动脉综合征 炎症 生化标志物 Acute coronary syndrome Inflammation Biomarkers
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