期刊文献+

美林治疗早产儿动脉导管未闭临床观察

暂未订购
导出
摘要 目的:观察美林关闭早产儿动脉导管的效果。方法:将生后2 ̄7天经超声心动图确诊的动脉导管未闭(PDA)早产儿52例口服美林作为观察组,另外45例未使用美林的PDA早产儿为对照组,统计动脉导管关闭率及副作用发生情况。结果:观察组PDA关闭率94.2%,高于对照组65.3%,差异有统计学意义(P<0.01);观察组无1例发生少尿、大便隐血阳性、血肌酐、尿素氮升高、肺动脉血流减少,肺动脉压力升高3例,喂养不耐受5例。结论:口服美林治疗早产儿PDA是行之有效的方法,且副作用小。
出处 《交通医学》 2007年第1期77-77,79,共2页 Medical Journal of Communications
  • 相关文献

参考文献5

  • 1Heyman E,Morag I,Batash D,et al.Closure of patent ductus arteroisus with oral ibuprofen suspension in premature newborn:a pilot study[J].Pediatrics,2003,112(5):354.
  • 2Dani C,Bertini G,Reali MF,et al.Prophylaxis of patent ductus arteriosus with ibuprofen in premature infants[J].Acta paediatr,2000,89(11):1369-1374.
  • 3王晨,王丹华.动脉导管未闭的药物治疗进展[J].新生儿科杂志,2005,20(2):91-94. 被引量:9
  • 4De Carolis MP,Romagnoli C,Polimeni V,et al.Prophylactic ibuprofen therapy of patent ductus arteriosus in preterm infants[J].Eur J Pediatr,2000,159(5):364-368.
  • 5Goumay V,Savagner C,Thiriez G,et al.Pulmonary hypertension after ibuprofen prophylaxis in very preterm infants[J].Lancet,2002,360(9331):492.

二级参考文献40

  • 1Narayanan M, Cooper B, Weiss H, et al. Prophylactic indomethacin : factors determining permanent ductus arteriosus closure. J Pediatr, 2000, 136(3): 330-337.
  • 2Fowlie PW, Davis PC. Prophylactic indomethacin for preterm infants: a systematic review and meta - analysis. Ach Dis Child Feud Neonatal Ed, 2003, 88(6): F464-466.
  • 3Merit LR, Vohr B, Allan W, et al. Outcome of children in the indomethaein intraventricular hemorrhage prevention trial.Pediatrcs, 2000, 105: 485-491.
  • 4Van Overmeire B, Koen Smets, Lecoutere D, et al. A comparison of ibuprofen and indomethacin for closure of patent ductus arteriosus. N Engl J Med, 2000, 373 : 674 - 681.
  • 5Van Overmeire B, Van de Broek H, Van Laer P, et al. Early versus late indomethacin treatment for patent ductus arteriosus in premature infants with respiratory, distress. J Pediatr,2001, 138(2): 205-211.
  • 6Keller RE,, Clyman RI. Persistent Doppler flow predicts lack of response to multiple copses of indomethacin in premature infants with recurrent patent ductus arteriousus. Pediatrics,2003, 112: 583-587.
  • 7Ojala R, Ala - Houhala M, Ahonen S, et al. Renal follow up of premature infants with and without perinatal indomethacin exposure. Arch Dis Child Fetal Neonatal Ed, 2001, 84( 1 ) :F28 - F33.
  • 8Hesono S, Ohno T, Kimoto H, et al. Reduction in blood glucose values following indomethaein therapy for patent ductus arteriosus. Pediatr Int, 1999, 41(5): 525-528.
  • 9De Carolis MP, Romagnoli C, Polimeni V. et al. Prophylactic ibuprofen therapy of patent ductus arteriosus in preterm infants. Eur J Pediatr, 2000, 159(5) : 364 - 368.
  • 10Dani C, Bertini G, Reali MF, et al. Prophylaxis of patent ductus arteriosns with ibuprofen in premature infants. Acta paediatr, 2000, 89(11): 1369-1374.

共引文献8

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部