摘要
本文以苯的新型生物学指标粘康酸为对照，评估了尿酚在不同苯接触浓度下的生物学监测效果。选择了三个接触不同苯浓度范围工厂内的３２６名工人为研究对象。结果三个工厂受检者接触苯浓度的范围与几何均值分别为０．２９～８．６７ｍｇ／ｍ３、３．１２～５６．８７ｍｇ／ｍ３、１７．２５～３６８．５２ｍｇ／ｍ３与２．５３ｍｇ／ｍ３、２１．０１ｍｇ／ｍ３、９４．０７ｍｇ／ｍ３。而尿酚与空气苯的相关系数分别为０．６１０７、０．７２４５、０．８０１４。相应粘康酸与空气苯的相关系数分别为０．８２１３、０．９１０７、０．８６５１。此结果说明尿酚在接触苯浓度较低时，难以反映内吸收情况。而粘康酸则能敏感地反映接触较低苯浓度环境时个体的内吸收剂量。
he value of urinary phenol in biological monitoring of benzene exposers under various concentrations was evaluated Urinary trans,trans muconic acid level was simultaneously used for comparison 326 workers of three factories exposed to various benzene concentrations were studied The results showed that personal benzene exposure concentration range and gemetric mean were respectively 0 29～8 67mg/m 3,3 12～56 87mg/m 3,17 25～368 52mg/m 3 and 2 53mg/m 3,21 01mg/m 3,94 07mg/m 3 in three factories The correlation coefficients between urinary phenol and personal air benzene in three factories were 0 6107,0 7245,0 8014 respectively,whereas corresponding values between trans,trans muconic acid and personal air benzene were 0 8213,0 9107,0 8651 respectively It is suggested that urinary phenol could not reflect internal benzene exposure dose when exposed to low benzene,but trans,trans muconic acid could do
出处
《职业医学》
1996年第5期8-10,共3页
China Occupational Medicine
关键词
尿酚
苯
粘康酸
监测
urinary phenol,benzene,trans,trans muconic acid,biological monitoring
