摘要
目的探讨谷氨酰胺(Gln)强化的全肠外营养(TPN)对大肠肿瘤患者术后的作用。方法将40例大肠癌患者随机分为Gln-TPN组和常规TPN组。检测体重、肝肾功能、氮平衡(NB)、血浆白蛋白水平(Alb)、术后疲劳评分等各项指标的变化。结果两组病人术后体重、肝肾功能比较无统计学意义。术后Gln-TPN组白蛋白水平高于常规TPN组(P<0.01);氮平衡明显改善,与常规TPN组相比差异显著(P<0.01);主观感觉好于常规TPN组(P<0.05)。结论Gln-TPN组比常规TPN组有利于术后负氮平衡的改善及血浆白蛋白的恢复,减少术后并发症,并能显著改善术后疲劳。
Object To investigate the effect of glutamine - intensified TPN in the postoperative patients with colorectal carcinoma. Methods 40 patients were divided into two groups including glutamine - supplemented TPN group and standard TPN group. Body weight, hepatic and renal functions , nitrogen balance, plasma concentrations of albumin and score of postoperative fatigue were tested . Results Body weight, hepatic and renal functions in two groups after operation no significant difference was showed between them . the concentration of albumin of glutamine - supplemented TPN group was higher than standard TPN group （P 〈 0.01 ）. nitrogen balance was better in glutamine -supplemented TPN group, there were significantly difference（ P 〈 0.01 ）. score of postoperative fatigue of glutamine - supplemented TPN group was better than standard TPN group （P 〈 0.05 ）. Conclusion The treatment of glutamine - supplemented TPN can improve the effect of total parenteral nutrition on the patients with colorectal carcinoma.
出处
《社区医学杂志》
2007年第02S期31-32,共2页
Journal Of Community Medicine
关键词
大肠肿瘤
谷氨酰胺
肠外营养
Colorectal carcinoma
Glutamine
Total parenteral nutrition
