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免疫组化方法在诊断肠神经异常性疾病中的应用进展 被引量:1

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摘要 2005年举行的第4届国际先天性巨结肠及其相关神经嵴病专题研讨会将先天性巨结肠、肠神经元性发育异常(intestinal neuronal dysplasia,IND)、肛门内括约肌神经性失弛缓症(Internal Anal Sphincter Neurogenic Achalasia,IASNA)、神经节细胞减少症统称为肠神经元异常(Intestinal Dysganglionoses,IDs)。这类疾病是小儿便秘的常见原因,症状相似,病理学特征不同。通过病理学方法检出标本中的神经节细胞,了解其发育情况并将其大小量化对于诊断肠神经元异常性疾病具有重要意义。目前病理学方法有很多,临床上最常用的是HE染色和AchE染色,但由于HE染色对于未成熟的神经节细胞检出率不高,且受到病理技师个人水平的影响;
出处 《临床小儿外科杂志》 CAS 2007年第1期54-56,共3页 Journal of Clinical Pediatric Surgery
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