摘要
目的:探讨糖皮质激素对急性中耳炎(AOM)中耳积液的疗效。方法:以43例(43耳)有明显鼓室压图异常的AOM患者为对象,采用前瞻性随机对照研究,对其中的23例(23耳)使用地塞米松加头孢呋辛钠进行治疗(试验组),另外20例(20耳)仅使用头孢呋辛钠进行治疗(对照组),随访治疗后鼓室压图的变化。结果:对照组鼓室压图恢复正常的时间为(54.6±6.2)d,试验组的时间为(38.5±6.1)d,经t检验2组间差异有统计学意义(P<0.05);在治疗后3个月,试验组的鼓室压图恢复率高于对照组。结论:糖皮质激素对AOM急性期中耳积液有明显的改善作用,可明显缩短中耳积液的时间,且对长程或慢性的中耳积液有一定的改善作用,是一种有效的辅助治疗方法。
Objective： To investigate the curative effect of corticosteroid on acute otitis media （AOM） with middle ear effusion. Method：Forty-three children （43 ears） with AOM and abnormal tympanogram were enrolled in a prospective, randomized trial. Twenty-three cases （23 ears） were treated with Dexamethasone and Cefuroxime Sodium, while the other 20 cases （20 ears） were only treated with Cefuroxime Sodium. Result：The period of normalization of tympanometric findings in Dexamethasone treatment group was （54.6 ± 6.2） days, which was much longer than that in the group without Dexamethasone treatment（38.5 ±6.1）. Three months after treatment, the curative rate of Dexamethasone treatment group was higher than that of the group without Dexamethasone treatment. Conclusion ：Corticosteroid can obviously improve middle ear effusion and shorten the duration of middle ear effusion of AOM in the first 2 weeks. To some extent, corticosteroid can also improve middle ear effusion in long term. It indicates that corticosteroid be used as an effective adjunctive drug in treating AOM with middle ear effusion.
出处
《临床耳鼻咽喉头颈外科杂志》
CAS
CSCD
北大核心
2007年第4期167-168,共2页
Journal of Clinical Otorhinolaryngology Head And Neck Surgery
关键词
中耳炎
糖皮质激素
中耳积液
Otitis media
Corticosteroid
Middle media effusion
