摘要
在致病因素的作用下,各种消化酶和细胞因子、活性氧簇、内毒素、NF-κB等炎症介质的生成增加以及它们之间的相互作用,共同造成胰腺和远处器官的损伤。急性胰腺炎的治疗以一般治疗、抗氧化剂、生长抑素、糖皮质激素治疗为主,NBD多肽是研究的重点。
With the role of causative agent, the increase and interaction of various kinds of digestive enzymes and inflammation mediators such as eytokines, reactive oxygen species （ ROS）, endotoxin, NF-κB resulted in the injury of pancreas and distant organ. The treament of acute pancreatitis is based on general treatment, antioxidant, somatostatin and glucocorticoid. The NF-κB essential modifier binding domain peptide which is newly developed becomes the emphasis of treament research.
出处
《国际病理科学与临床杂志》
CAS
2007年第1期68-72,共5页
Journal of International Pathology and Clinical Medicine
基金
广东省自然科学基金立项课题(A04009624)~~
关键词
急性胰腺炎
发病机制
治疗
acute pancreatitis
athogenesv
treatment
