摘要
动脉粥样硬化斑块的不稳定导致冠心病特殊疾病谱——急性冠状综合征的发生。炎症机制在动脉粥样硬化斑块的发生、发展中扮演重要角色。近年来,不断有研究证实前炎症因子白介素-18密切参与了此过程,并且与急性冠状动脉综合征的发生有着极强的关联。
As has been known to us, instability of atherosclerotic plaque leads to the development of clinical acute coronary syndrome. Inflammation has been proved to play an important role in the initiation and progression of atherosclerotic plaque. More recently, emerging study has confirmed this concept that the proinflammatory factor interleukin-18 is intimately involved in the above mentioned process and extremely associated with the development of the acute coronary syndrome. This article will review the relationship between interleukin-18 and acute coronary syndrome, and its prospect in clinical setting.
出处
《国际病理科学与临床杂志》
CAS
2007年第1期57-59,共3页
Journal of International Pathology and Clinical Medicine
