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芬太尼复合小剂量左旋布比卡因在腰硬联合麻醉剖宫产的临床应用 被引量:5

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摘要 目的探讨小剂量左旋布比卡因复合芬太尼或舒芬太尼在腰硬联合麻醉下剖宫产手术的临床效果。方法腰硬联合麻醉下行剖宫产手术60例,ASA Ⅰ~Ⅱ级,年龄20~35岁,按照随机对照表分为两组:芬太尼组(F组)用0、75%左旋布比卡因1ml加芬太尼25μg(0.5m1)加10%葡萄糖1ml(总量2.5m1),舒芬太尼组(S组)用0.75%左旋布比卡因1ml加舒芬太尼2.5μg(0.5m1)、10%葡萄糖lml(总量2.5m1),注入蛛网膜下腔。观察两组的血流动力学变化(血压、心率、血氧饱和度),给药后产妇的感觉阻滞时间的比较,术后有效镇痛时间,术后改良Bromage运动阻滞评分,不良反应及新生儿出生后Apgar评分。结果两组的血流动力学稳定,血压下降不明显,两组各有1例需用麻黄碱升压处理,两组心率下降均不明显,S组有1例心率低于55次/min需用阿托品纠正。两组的感觉阻滞时间差异无统计学意义。术中镇痛完全,且肌松良好,均未追加镇痛药物。术后s组有效镇痛持续时间较F组长,差异有统计学意义。术后改良Bromage运动阻滞评分:两组集中在2~3分,此外各有2例为4分。新生儿出生后Apgar评分两组差异无统计学意义。两组不良反应发生率亦无显著性差异,均无呼吸抑制发生。结论小剂量左旋布比卡因复合芬太尼或舒芬太尼在腰硬联合麻醉剖宫产手术中,对血流动力学影响小,镇痛完全,术后患者能及早运动,不良反应小,舒芬太尼复合组术后有效镇痛时间较长。
出处 《重庆医学》 CAS CSCD 2007年第5期457-459,共3页 Chongqing medicine
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