摘要
目的探讨持续不卧床腹膜透析(CAPD)、血液透析滤过(HDF)对并发难治性高血压的单纯规律血液透析(HD)患者的临床疗效。方法68例HD伴难治性高血压患者随机分为CAPD、HDF/HD两组。CAPD组每天腹透液总量8000ml,晚上留腹2000ml;HDF/HD组每周采用2次血液透析加1次血液透析滤过治疗,治疗时间为3个月。比较两组患者治疗前后平均动脉压、BUN及Cr的变化。结果与治疗前相比,治疗后两组平均动脉压水平、BUN与Cr水平均较治疗前明显下降,其差异有统计学意义(P<0.05)。治疗后CAPD组与HDF/HD组相比,平均动脉压水平亦明显下降,其差异有统计学意义(P<0.05);但BUN与Cr水平两组相比无统计学意义(P>0.05)。结论对于尿毒症难治性高血压患者血压的控制HDF/HD与CAPD均为有效的治疗方法,但CAPD效果更佳。
Objective To evaluate the clinical effects of different blood purification methods on hypertension patients with endostage renal failure. Methods Sixty-eight hypertension paitents with endo-stage renal failure were divided into 2 groups at random, continuous ambulatory peritoneal dialysis group （CAPD）, hemodiafiltration and hemodialysis group （HDF/HD）. The volume dose of peritoneal dialysis fluid for CAPD group was 8000ml, which contained 2000ml remaining at night. The patient in HDF/HD group underwent 2 hemodialysis and 1 hemodiafiltration every week for 3 months. Mean arterial pressure （MAP）, BUN, Cr were observed and compared before and after the course of treatment of each patient. Results Compared with that of pre-therapy, levels of MAP, BUN or Cr fell significantly after treatment （P〈0. 05）. MAP level of CAPD group fell more obviously than that of HDF/HD group, statistical significance were observed between the 2 groups after the treatment, however, no significance were detected between the two groups in BUN or Cr levels （P〉0.05）. Conclusion Both CAPD and HDF/HD are effective treatment, and CAPD is a much better way for hypertension patients with endo-stage renal failure.
出处
《重庆医学》
CAS
CSCD
2007年第5期426-427,共2页
Chongqing medicine
