摘要
[目的]揭示广东省护理人员职业接触化疗药物后产生的妊娠并发症及妊娠结局的现状。[方法]从广东省的“一甲”“二甲”和“三甲”各10所医院抽取接触化疗药物的已婚护士379名(孕次486次)为接触组;非接触化疗药物的已婚护士399名(孕次454次)为对照组。回顾性调查分析两组护士接触化疗药物情况、妊娠并发症(先兆流产、剧烈呕吐、贫血、妊娠高血压综合征)和妊娠结局(足月产、自然流产、早产、死胎产、宫外孕、先天畸形)。[结果]接触组护士妊娠并发症除妊娠高血压综合征外均显著高于对照组(P<0.001);妊娠结局中足月产率对照组显著高于接触组(P<0.001);自然流产、死胎产、先天畸形接触组显著高于对照组(P<0.05)。[结论]职业接触化疗药物先兆流产、妊娠剧烈呕吐、妊娠贫血及自然流产、死胎产、先天畸形发生的危险性增加。
Objective： To reveal the status quo of gestational complications and pregnancy outcome of nursing staffs caused by their occupational contacting of chemotherapeutic drugs in Guangdong province. Methods： A total of 379 married nurses （486 gravidities） who have contacted chemotherapeutic drugs were selected from the first, the second and the third level grade A hospitals （ 10 hospital of each level） as contacting group. Another 399 married nurses （454 gravidities） who have not contacted chemotherapeutic drugs from the same hospitals were selected as control group. The status quo of contacting chemotherapeutic drugs, gestational complications （threatened abortion, anacatharsis, anemia, pregnancy induced hypertension syndrome） and pregnancy outcome （term birth, spontaneous abortion, premature delivery, fetal death, exfetation, congenital deformity） of all nurses of the two groups were investigated retrospectively. Results： The incidences of gestational complications of nurses in contacting group were much higher than that of nurses in control group except pregnancy- induced hypertension syndrome （P〈 0. 001 ）. The rate of full term birth in pregnancy outcome of nurses in control group was much higher than that of nurses in contacting group （P 〈 0. 001 ）. The incidence of spontaneous abortion, fetal death and congenital deformity in nurses of contacting group were much higher than that in nurses of control group （P 〈 0.05）. Conclusion： The risk of threatened abortion, anacatharsis, anaemia and spontaneous abortion, fetal death, and congenital deformity in pregnant nurses of occupational contacting with chemotherapeutic drugs is increased.
出处
《护理研究（上旬版）》
2007年第2期322-323,共2页
Chinese Nursing Researsh
关键词
化疗药物
职业暴露
妊娠并发症
妊娠结局
chemotherapeutic drugs
occupational exposure
gestational complications
pregnancy end - results
