摘要
目的观察“盆痛灵”方治疗子宫内膜异位症(简称EM)盆腔痛的临床疗效及其对血栓烷B(2TXB2)、6-酮-前列腺素F1(α6-Keto-PGF1α)的影响。方法采用盆痛灵方水煎剂直肠给药治疗EM盆腔痛患者30例,观察用药前后临床症状的改善情况,并在治疗前后采用放免法测定血浆TXB2、6-Keto-PGF1α的浓度。结果近期治愈3例,显效16例,有效9例,无效2例,总有效率为90%,且治疗前经期血浆TXB2、6-Keto-PGF1α水平均增高,中药盆痛灵可显著降低两者水平。结论盆痛灵有明显的镇痛作用,其作用机理可能与改善TXB2、6-Keto-PGF1α水平,协调子宫肌层的活动有关。
Objective To observe the clinical effects of ＂Pentongling Decoction＂ in the treatment of pelvic pain following endometriosis and its influence on TXB2 and 6-Keto-PGF1α. Methods Thirty subjects were rectally given the Decoction. The clinical symptoms, TXB2 and 6- Keto-PGF1α were observed before and after treatment. Results Three cases got near-term cure, 16 cases marked effectiveness, 9 cases effectiveness and 2 cases failure; the total effective rate was 90%. TXB2 and 6-Keto-PGF1α dropped after treatment. Conclusion ＂Pentongling Decoction＂ has significant effects on pelvic pain, possibly by decreasing TXB2 and 6-Keto-PGF1α.
出处
《上海中医药杂志》
北大核心
2007年第3期35-36,共2页
Shanghai Journal of Traditional Chinese Medicine
基金
上海中医药大学科学技术基金项目
