摘要
目的:探讨宫颈上皮内瘤变(CIN)的诊断及对治疗的影响。方法:对2003年在我院诊断为CIN的190例患者的术前宫颈多点活检、术中快速病理诊断、术后组织学结果及治疗方法等资料进行回顾性分析。结果:术前宫颈多点活检的过低诊断率为8.0%(肉眼下多点活检11.8%、阴道镜下多点活检2.2%),漏诊浸润癌3例;术中快速病理诊断后过低诊断率降至4.5%,无浸润癌漏诊。对CINⅠ和CINⅡ、Ⅲ的过度治疗率分别为21.7%和38.0%。结论:阴道镜下多点活检可以提高诊断准确性,术中宫颈锥切或再次多点活检行快速病理诊断可减少对宫颈癌及CIN的过低诊断,有利于选择恰当的治疗方法。
Objective：To explore the reasonably diagnostic and therapeutic program of cervical intraepithelial neoplasia （CIN） .Methods：One hundred and ninety paUenls with cervical intraepithelial neoplasia diagnosed and treated at West China Second University Hospital of Sichuan university in 2003 were retrospectively analyzed,focusing on clinical management of cervical intraepithelial neoplasia and analyze pathological finding in preoperative multiple punch biopsies,intraoperative frozen section examinations. Results：The of under-diagnosis rate of preoperative multiple punch biopsies was 8.0% （11.8% directed by the naked eye,2.2% with colposcopy）,three cases of invasive cancer were missed. After frozen section examination intraoperation used, the rate of under-diagnosis decreased to 4.5% and no case of invasive cancer was missed.The rateofover-treatment to CINⅠ and CINⅡ/Ⅲ were21.7% and 38.0%, respectively. Conclusions： The accuracy of colposcopically directed biopsy is satisfactory. Frozen section examination intraoperation or once again multiple punch biopsies can decrease under-diagnosi of invasive cervice carcinoma and intraepithelial neoplasia, and can prevent parthy over-treatment to cervical intraepithelial neopiasia.
出处
《实用妇产科杂志》
CAS
CSCD
北大核心
2007年第2期103-105,共3页
Journal of Practical Obstetrics and Gynecology
关键词
宫颈上皮内瘤变
诊断
治疗
Cervical intraepithelial neoplasia
Diagnosis
Management
