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燃煤型砷中毒患者血红蛋白及核黄素和抗坏血酸的水平

An Analysis on Levels of Hemoglobin,Riboflavin,Ascorbic acid in Sufferers of Arsenism Caused by Coal-burning
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摘要 目的:进一步探讨燃煤型砷中毒患者营养状况及与病情的关系。方法:用毫克分子消光系数法测定血红蛋白(Hb)浓度,荧光法测定4 h负荷尿中核黄素(VB2)及抗坏血酸(Vc)的排出量来评价患者的营养水平。结果:患者中贫血发生率达82.0%,96.0%患者体内VB2缺乏,而有24.0%的患者Vc也处于缺乏状态,与正常对照相比,差异有显著性。结论:燃煤型砷中毒患者体内存在严重核黄素缺乏和抗坏血酸的不足,与砷中毒病情的发生和发展有关。 Objective: To investigate the relation between the nutritional level of arsenic sufferers and their disease condition, so as to provide scientific basis for further nutrition-poisoning study. Methods: Hemoglobin density was measured with milligram molecule extinction coefficient method, and the amounts of ascorbic acid (Vc) and riboflavin ( VB2) VB2 in 4-hour discharges of urine were measured with fluorescent method. The sufferers' nutritional levels were evaluated. Results: Among the sufferers, 82.0% of them had anemia, 96.0% had vitamin VB2 deficiency, and 24.0% vitamin C deficiency. The differences between the nutritional levels of arsenism sufferers and healthy controls were statistically significant. Conclusion : Serious deficiency of Vc and VB2 occurs in these sufferers, which might be relative to the development of this disease.
出处 《贵阳医学院学报》 CAS 2007年第1期48-49,52,共3页 Journal of Guiyang Medical College
关键词 砷中毒 血红蛋白类 核黄素 抗坏血酸 arsenic poisoning hemoglobins riboflavin ascorbic acid
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