摘要
目的通过对２０例老年恶性淋巴瘤患者治疗前后磁共振成像（ＭＲＩ）信号强度的变化，来标定治疗后肿瘤组织纤维化的程度，从而对疗效作出准确地评估。方法应用ＭＲＩ系统的自动测量装置，在治疗前后分别测量肿瘤、皮下脂肪及肌肉的信号强度，将肿瘤的信号强度分别被脂肪和肌肉的相应测量值除，得到标准化值。结果第１次治疗后肿瘤被脂肪和肌肉标准化后的信号强度的均数及标准差分别为０．５±０．３和１．９±１．３；第２次治疗后分别为０．７±０．２和３．０±１．３，比治疗前的标准化值明显减小（Ｐ值＜０．０１）。结论ＭＲＩ信号强度的测量可准确评估淋巴瘤的疗效，ＭＲＩ的Ｔ２加权图像可对纤维化组织和残留或复发的肿瘤组织作出鉴别。
Objective To evaluate the curative effect accurately is the key of successful treatment of malignant lymphoma. In this study, the fibrotic degrees of tumors in 20 treated malignant lymphoma patients were measured by comparing signal intensity of magnetic resonance imaging(MRI).Methods By using the automatic measurement system of MR, the signal intensities of tumors, subcutaneous fat and muscles were measured before and after treatment. The standardized value was obtained by dividing the signal intensity of tumor with that of fat and muscle. Results After first course of treatment, the standardized values of tumor to fat and tumor to muscle were 0.5±0. 3 and 1. 9± 1. 3;After second course of treatment, they were 0. 7±0. 2 and 3. 0±1. 3. They were decreased obviously than those before treatment(P<0. 01). Conclusions The measurement of MRI signal intensity can accurately evaluate the curative effect of malignant lymphoma; T_2-weighted images of MRI were most helpful in distinguishing fibrotic tissue from recurrent tumor tissue.
出处
《中华老年医学杂志》
CAS
CSCD
北大核心
1996年第4期217-219,共3页
Chinese Journal of Geriatrics
关键词
淋巴瘤
诊断
磁共振成像
老年人
治疗
mediastinal tumor lymphoma magnetic resonance imaging
