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Sonic hedgehog信号通路在肺发育及肺癌发生中的意义 被引量：1

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摘要 在胎肺的发育过程中,支气管上皮细胞和间质之间的通讯联系对胎肺的正常形态构筑以及功能成熟都起到了重要的调控作用。Sonic hedgehog信号通路(Shh信号通路)则在这种联系中发挥着重要作用,其与其他细胞因子相互协调,形成了上皮与间质间调节作用的网络,确保了胎肺的正常发生和发育。近年来,在一些肺癌组织中也发现了Shh信号通路的异常激活,提示Shh信号通路在肺癌的发生发展过程中可能也起到了一定的作用。
作者 张大勇 黄中新
机构地区 暨南大学医学院组织胚胎学教研室
出处 《解剖学研究》 CAS 2007年第1期68-72,共5页 Anatomy Research
关键词 SHH信号通路 胎肺 肺癌
分类号 R734.2 [医药卫生—肿瘤]
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参考文献34

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二级参考文献32

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共引文献10

同被引文献11

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解剖学研究
2007年 第1期

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