摘要
目的探讨小切口无缝线深板层角膜内皮移植术的手术方法、临床疗效及并发症的预防与处理。方法对9例（9只眼）大泡性角膜病变患者行小切口无缝线深板层角膜内皮移植术，其中6例联合前段玻璃体切割术。术后观察植片与植床贴合情况、植片移位的发生和处理。随访3～5个月，观察视力、植片透明度、角膜曲率、角膜散光及角膜内皮细胞密度。结果8例患者植片与植床贴合良好，1例患者术后第1天植片移位，经再次复位后贴合良好。6例患者不同程度提高视力，3例患者因术前长期高眼压，术后视力不提高。9例患者植片均透明，角膜曲率（43．96±3．38）D，角膜散光度数（3．32±1．20）D，角膜内皮细胞密度（2124±278）个／mm^2，未出现严重并发症。结论与穿透性角膜移植或板层角膜瓣下深板层角膜内皮移植术比较，小切口无缝线深板层角膜内皮移植术治疗大泡性角膜病变更有优势，有望成为治疗该病的手术方式之一。
Objective To investigate the surgical procedure, clinical efficacy, and the prevention and management of complications of sutureless, small-incision deep lamellar endothelial keratoplasty （DLEK）. Methods Nine patients （nine eyes） with bullous keratopathy underwent suturelass, smallincision DLEK surgery, six of them was combined with anterior vitrectomy. Visual acuity, graft clearance, corneal curvature, astigmatism and endothelial cell density （ECD） were observed over a 3-5 month follow-up period. Results All grafts remained transparent, and six eyes had improved visual acuity. After the surgery, mean corneal curvature was （43.96 ± 3.38 ） D. Mean corneal astigmatism was （ 3.32 ± 1.20 ） diopter（D）. Mean ECD was （2124 ± 278 ）cells/mm^2. No severe complications occurred. Conclusion Sutureless, small-incision DLEK, as compared with penetrating keratoplasty （PKP） and microkeratomeassociated deep lamellar endothelial keratoplasty, has more advantages and is expected to be the initial surgical treatment for bullous keratopathy.
出处
《中华眼科杂志》
CAS
CSCD
北大核心
2007年第2期118-123,共6页
Chinese Journal of Ophthalmology
基金
广东省科技计划资助项目（2004840501008）,（20051150301013）
关键词
角膜移植
角膜疾病
预后
Corneal transplantation
Corneal diseases
Prognosis
