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甲宁方治疗肝阳上亢、血瘀痰凝型甲状腺功能亢进症31例临床观察 被引量:6

Clinical effect of Jianing Prescription in treating hyperthyroidism in 31 patients with hyperactivity of liver-yang and blood stasis and phlegm coagulation
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摘要 [目的]观察甲宁方对肝阳上亢、血瘀痰凝证甲状腺功能亢进症的治疗效果。[方法]将临床诊断为甲状腺功能亢进症,中医证属肝阳上亢、血瘀痰凝证的患者31例纳入治疗组,给予甲宁方治疗,8周为1个疗程,进行治疗前后对照比较。[结果]甲宁方能有效改善患者三碘甲状腺原氨酸(T3)、甲状腺激素(T4)、游离三碘甲状腺原氨酸(FT3)、游离甲状腺素(FT4)、促甲状腺素(TSH)等指标,治疗前后比较有显著性差异(P<0.05)。并且有促进甲状腺刺激抗体(TSAb)转阴的作用。[结论]临床观察表明甲宁方治疗肝阳上亢、血瘀痰凝证甲状腺功能亢进症疗效满意并具有改善甲状腺功能,调节免疫的作用,且无明显不良反应。 [Objective] To observe the therapeutic effect of Jianing(calming thyroid) Prescription in treating hyperthyroidism with hyperactivity of liver-yang and blood stasis and phlegm coagulation. [Methods] Thirty-one patients consisting with above diagnosis were enrolled into the treatment group treated with Jianing Prescription. After a treatment course of eight weeks the therapeutic effect was compared before and after therapy. [Results] Jianing Prescription could effectively improve the parameters T3, T4, FT3, FT4, TSH and so on in patients with significant difference before and after treatment(P〈0.05). The prescription had also effeet of transforming the positive TSAb to negative. [Conclusions] Jianign Prescription has satisfactory effect in treating hyperthyroidism with hyperactivity of liver-yang and blood stasis and phlegm coagulation. It ean improve the thyroid function, regulate the immunology without adverse effect.
出处 《天津中医药》 CAS 2007年第1期25-26,共2页 Tianjin Journal of Traditional Chinese Medicine
基金 天津市卫生局中医 中西医结合基金资助(03045)。
关键词 甲宁方 肝阳上亢 血瘀痰凝证 甲状腺功能亢进症 临床观察 Jianing prescription hyperactivity of liver-yang and blood stasis and phlegm coagulation hypeahyroidism clinical observation
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参考文献3

  • 1陈灏珠.实用内科学[M](第12版)[M].北京:人民卫生出版社,2005.348-351.
  • 2中华人民共和国卫生部.中药新药临床研究指导原则[s].北京:人民卫生出版社,1993.28~30.
  • 3Chazenbalk GD,Wang Y,Guo J,et al.A mouse monodonal antibody to a thyrotropin receptor ectodomain variant provides insight into the exquisite antigenic conformational requirement,epitopes and in vivo concentration of human autoantibodies[J].J Clin Endocrinol Metab,1999,84:702-710.

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