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含锶磷酸钙骨水门汀的理化性能和水化产物 被引量:1

Physicochemical Properties and Hydrating Product of Strontium-Containing Hydroxyapatite Cement
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摘要 目的探讨用碳酸锶对α-磷酸钙骨水门汀系统进行改性后的理化性能和水化产物分析。方法在α-磷酸钙骨水门汀粉末中加入碳酸锶改性,考察其凝固时间、压缩强度、溶解率及pH值的变化,采用X射线衍射、红外光谱、扫描电镜分析其水化产物及表面形貌。结果添加适量的碳酸锶不会妨碍α-磷酸三钙(-αTCP)的水化进程,凝固时间适于临床操作,压缩强度和溶解率增大,水化反应后呈弱碱性,水化产物为含锶的缺钙型碳酸基HA。结论适量的碳酸锶可改善α-磷酸钙骨水门汀系统的理化性能,水化产物与天然骨组织的矿物相成分接近,可能有利于植入材料与骨的结合。 Objective The physicochemical properties and hydrating product of α-tricalcium phosphate cement modified by strontium carbonate was investigated. Methods In this study α-tricalcium phosphate(α-TCP) cement was modified by strontium carbonate, the setting-time, compressive strength, rate of dissolution and value of pH were investigated. The hydrating product was analyzed by X-ray diffraction infrared spectum and electron microscope. Results Strontium carbonate had no interference with α-TCP cement's hydrating process. The setting-time could meet the expectation of clinical operation. The compressive strength and the rate of dissolution increased. The hydrating product was deficiency calcium hydroxyapatite containing with strontium ions. Conclusion Proper Strontium carbonate could improve the property of α-tricalcium phosphate cement. The hydrating product was similar to nature bone and easy to connect with bone.
出处 《福建医科大学学报》 2007年第1期39-42,共4页 Journal of Fujian Medical University
基金 国家863计划资助项目(2002AA326080) 福建省自然科学基金资助项目(C0410024)
关键词 磷酸钙 碳酸 calcium phosphate carbonic acid strontium
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参考文献8

  • 1Blom E J,Klein-Nulend J,Wolke J G,et al.Transforming growth factor-beta1 incorporation in an alpha-tricalcium phosphate/dicalcium phosphate dihydrate/tetracalcium phosphate monoxide cement:release characteristics and physicochemical properties[J].Biomaterials,2002,23(4):1261-1268.
  • 2顾云峰,廖大鹏,周正炎,周慧峰,陈德敏.锶磷灰石修复颌骨缺损的实验研究[J].中华口腔医学杂志,2001,36(4):262-265. 被引量:6
  • 3Ni G X,Lu W W,Xu B,et al.Interfacial behaviour of strontium-containing hydroxyapatite cement with cancellous and cortical bone[J].Biomaterials,2006,27(29):5127-5133.
  • 4Wong C T,Chen Q Z,Lu W W,et al.Ultrastructural study of mineralization of a strontium-containing hydroxyapatite(Sr-HA) cement in vivo[J].J Biomed Mater Res A,2004,70(3):428-435.
  • 5Guo D,Xu K,Zhao X,et al.Development of a strontium-containing hydroxyapatite bone cement[J].Biomaterials,2005,26(19):4073-4083.
  • 6Khairoun I,Magne D,Gauthier O,et al.In vitro characterization and in vivo properties of a carbonated apatite bone cement[J].J Biomed Mater Res,2002,60(4):633-642.
  • 7Khairoun I,Boltong M G,Driessens F C,et al.Effect of calcium carbonate on the compliance of an apatitic calcium phosphate bone cement[J].Biomaterials,1997,18(23):1535-1539.
  • 8Bermudez O,Boltong M G,Driessens F C,et al.Chloride-and alkali-containing calcium phosphates as basic materials to prepare calcium phosphate cements[J].Biomaterials,1994,15(12):1019-1023.

二级参考文献1

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同被引文献11

  • 1Blom E J, Klein-Nulend J, Wolke J G, et al. Transforming growth factor-betal incorporation in an alpha-tricalcium phosphate/dicalcium phosphate dihydrate/tetracalcium phosphate monoxide cement: release characteriztics and physicochemical properties[J]. Biomaterials, 2002,23(4) : 1261-1268.
  • 2Ni G X,Lu W W,Xu B,etal. Interracial behaviour of strontium-containing hydroxyapatite cement with cancellous and cortical bone[J]. Biomaterials, 2006,27(29) :5127-5133.
  • 3Wong C T,Chen Q Z,Lu W W,etal. Uhrastructural study of mineralization of a strontium-containing hydroxyapatite (SrHA) cement in vivo [J]. J Biomed Mater Res A, 2004,70 (3) :428-435.
  • 4Guo D,Xu K, Zhao X,et al. Development of a strontium-containing hydroxyapatite bone cement[J]. Biomaterials, 2005, 26(19) :4073-4083.
  • 5Wang X, Ma J, Wang Y,et al. Structural characterization of phosphorylated chitosan and their applications as effective additives of calcium phosphate cements[J]. Biomaterlals, 2001, 22(16) :2247-2255.
  • 6Wang X,Ma J,Wang Y,etal. Bone repair in radii and tibias of rabbitz with phosphorylated chitosan reinforced calcium phosphate cements[J]. Biomaterials, 2002,23(21) :4167-4176.
  • 7Ambard A J, Mueninghoff L. Calcium phosphate cement: review of mechanical and biological properties [ J ]. Prosthodont, 2006,15 (5) : 321-328.
  • 8Khairoun I, Driessens F C, Boltong M G,et al. Addition of cohesion promotors to calcium phosphate cements[J]. Biomaterials, 1999,20(19) :393-398.
  • 9Bermudez O, Boltong M G, Driessens F C,et al. Chloride-and alkali-containing calcium phosphates as basic materials to prepare calcium phosphate cements[J]. Biomaterlals, 1994,15 (12) :1019-1023.
  • 10顾云峰,廖大鹏,周正炎,周慧峰,陈德敏.锶磷灰石修复颌骨缺损的实验研究[J].中华口腔医学杂志,2001,36(4):262-265. 被引量:6

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