摘要
目的探讨围手术期处理对三发性甲状旁腺功能亢进症(THPT)治疗效果的影响。方法报告1例肾移植后三发性甲状旁腺功能亢进症的诊治,结合国内外文献复习对其围术期处理进行回顾性分析总结。结果病人术前血钙3.08mmol/L,甲状旁腺素195pg/mL,切除3个甲状旁腺后甲状旁腺素快速下降超过50%,术后出现低血钙,甲状旁腺素低下,经补钙2月后血钙及甲状旁素恢复正常。结论三发性甲状旁腺功能亢进症在国内是一种少见病,部分需要手术治疗,重视围术期的处理是THPT的重要环节;对高血钙危象的有效治疗必须尽早开始,以保护移植肾功能和挽救病人生命。
[Objective] To examine the therapeutic effects of perioperative management for tertiary hyperparathyroidism （THPT）. [Methods] The diagnosis and treatment for one ease of a woman with tertiary hyperparathyroidism after kidney transplantation was reported, and the perioporative managements were analyzed retraspoctively by reviewing the literatures. [Results] The patient＇ s p＇arathyroid hormone （PTH） decreased to 50% rapidly after the removal of three parathyroids, the hypocalcemia and low of parathyroid hormone occur after operation. The hypocalcemia and low of parathyroid hormone return to normal by the supplementary calcium two months later. [Conclusions] Tertiary hyperparathyroidism was rarely reported in domestic literatures, among whom part of them need surgical treatment. It is necessary to emphasize porioperative management in treatment of tertiary hyperparathyroidism, and the immediate treatment must be considered in any patients with hypercalcemic crisis in order to protect the function of the allograft and to save the patient＇s life.
出处
《中国现代医学杂志》
CAS
CSCD
北大核心
2007年第2期233-235,237,共4页
China Journal of Modern Medicine
