摘要
目的:探讨纳洛酮抢救重度一氧化碳中毒患儿的临床疗效。方法:采用随机、对照实验,将重度一氧化碳中毒患儿入院后随机分成纳洛酮治疗组和对照组,观察患儿昏迷时间、后遗症及死亡情况。结果:治疗组平均昏迷时间(3.93±1.85)h,明显短于对照组(5.97±3.24)h,(P<0.01),两组后遗症及死亡情况无明显差异(P>0.05)。结论:纳洛酮能够加快重度一氧化碳中毒患儿苏醒,缩短昏迷时间。
Objective： To study the clinical effect of naloxone on children severely poisoned with carbon monoxide. Methods： 60 children of severe carbon monoxide poisoning were randomly divided into a control group （30 cases） and a naloxone treatment group （30 cases）. There was no significant difference between the two groups in the components of gender, age and the coma degree. And they were assessed for the time of coma, sequela and death. Results： There was significant difference in the time of coma between the two groups （the coma time was respectively 3.93 ± 1.85 hours and 5.97 ± 3.24 hours）. There was no significant difference in the sequela and death. Conclusions： The treatment of naloxone could improve the ]eve] of consciousness and shorten the time of coma in severe carbon monoxide poisoning.
出处
《儿科药学杂志》
CAS
2007年第1期46-48,共3页
Journal of Pediatric Pharmacy
关键词
中毒
一氧化碳
昏迷
纳洛酮
Polsoning
Carbon monoxide
Coma
Naloxone
