摘要
颈动脉分叉部动脉粥样硬化梗阻性疾病的起始与进展的血液动力学机制,在过去数十年被广泛研究。注意力集中在发现斑块最多的颈动脉球部或窦部。本文作者综述了颈动脉分叉部复杂的局部血液动力学改变,也包括了血液动力学改变所引起的特殊的细胞生物学反应的主要进展。这对于我们理解颈动脉窦部粥样硬化的血液动力学机制,改善血管内微创治疗与非创伤性治疗具有一定意义。
Hemodynamic mechanisms for the initiation and progression of carotid bifurcation atherosclerotic occlusive disease have been extensively researched during the past decades. Attention has focused on the carotid bulb,or sinus,where most atherosclerotic plaques are found. Herein, the authors review the seminal works that have led to an understanding of not only complex local hemodynamics but also the elicited specific biologic response.Understanding the role of hemodynamics in atherogenesis may lead to the improvement of minimally invasive endovascular therapy and noninvasive strategies.
出处
《中国医学物理学杂志》
CSCD
2007年第1期48-51,共4页
Chinese Journal of Medical Physics
基金
国家自然科学基金资助项目(编号:39970269)
关键词
颈动脉狭窄
动脉壁切应力
carotid stenosis
arterial wall shear stress（WSS）
