摘要
目的:总结儿童系统性红斑狼疮(SLE)的临床及实验室检查特点。方法:对本院51例住院患儿SLE的临床资料进行回顾性分析。结果:临床表现以肾损害(84.3%)、发热(70.6%)、皮疹(68.8%)、淋巴结肿大(41.2%)较常见。实验室检查以ANA(+)(92.0%)、补体降低(90.0%)、ESR升高(84.0%)、贫血(83.6%)较常见。病情活动性(SLEDAI积分)以轻至中度活动为主。结论:儿童SLE的临床表现多样化,应结合实验室检查进行分析,早期确诊,避免误诊,积极治疗。
Objective： To summarize the clinical and laboratory features of systemic lupus erythematosus in 51 pediatric cases. Methods： The clinical data of 51 cases of systemic lupus erythematosus in children were analyzed retrospectively. Results： The common clinical manifestations were renal damage（ 84.3% ）, fever（70.6% ）, skin rash （68.8%） ,and enlarged lymph nodes（41.2% ）. The common laboratory findings included positive anti-ANA antibody （90.0%） , depressed complement level（90.0% ） , quickened ESR（ 84.0% ）andanaemia （83.6%）. Activity in disease （SLEDAI score）in the most cases were at mild to moderate levels. Conclusion：The clinical manifestations of systemic lupus erythematosus in children are diverse. It is necessary to analyze in combination with laboratory findings, in order to get a sound diagnosis and active treatment.
出处
《广州医学院学报》
2006年第5期32-35,共4页
Academic Journal of Guangzhou Medical College
关键词
儿童
系统性红斑狼疮
临床特点
children
systemic lupus erythematosus
clinical features
