摘要
[目的]了解东莞市体检人群中乙肝病毒(HBV)感染情况与血清丙氨酸氨基转移酶(ALT)的异常率。[方法]对8 181名体检者应用酶联免疫吸附法(ELISA)测定HBsAg、HBsAb、HBeAg、HBeAb、HBcAb,用速率法测定ALT。[结果]HBsAg的阳性率为13.14%,HBeAg的阳性率为4.89%,ALT的异常率为3.40%。乙型肝炎病毒血清学标志物主要以HBsAg、抗-HBe、抗-HBc阳性和HBsAg、HBeAg、抗-HBc阳性的两种模式为主。[结论]东莞市体检者中的HBsAg的阳性率高于全国的HBsAg的阳性率,其中HBsAg阳性率20 a以下相对低些,20～30 a的HBsAg的阳性率高达17.19%,HBeAg的阳性率在20￣30 a的打工者中占较大比例。其人群分布与计划免疫、文化程度、卫生习惯、生活环境等因素有关。
[Objective] To be acquainted with the status of hepatitis B （HBV） infection and abnormal rate of alanine transferase （ALT） in general population in Dongguan. [ Methods] HBV markers including HBsAg, anti-HBs, HBeAg, anti-HBe, anti-HBc were measured by enzyme-linked immunosorbent assay and ALT was determined by kinetics method. [Results] The positive rates of HbsAg and HBeAg were 13.14% and 4.89%, respectively; the abnormal rate of ALT was 3.40%. The leading HBV maHbsAgers included two kinds of patterns： HBsAg, anti-HBe, anti-HBc positive, and the HBsAg, HBeAg, anti-HBc positive. [Conclusion] The positive rates of HBsAg in Dongguan is higher than that in the whole nation. The positive rates of HbsAg in population under 20 years is relative low to the other years .The positive rate of HBsAg between 20 to 30 years is 17.19%. The positive HBeAg distributes mainly in floating population between 20~30 years. The distribution of HBV markers is related to expanded program on immunization, culture level, health habit and living condition.
出处
《现代预防医学》
CAS
北大核心
2007年第2期353-354,共2页
Modern Preventive Medicine
