摘要
目的分析绵阳市慢性心力衰竭患者药物治疗动态,了解对心力衰竭患者规范化药物治疗水平。方法采用绵阳市3所医院1998、2001和2005年住院慢性心力衰竭患者病历数据库,对慢性心力衰竭患者使用药物治疗状况进行调查分析。结果绵阳市3家医院上述3年慢性心力衰竭患者共有2038人。1998、2001和2005年药物使用率分别是:利尿剂63.7%、68.1%和77.6%、洋地黄类40.2%、42.4%和68.6%、ACEI/ARB(血管紧张素转换酶抑制剂/血管紧张素受体拮抗剂)18.2%、30.3%和62.4%、β-blocker(β受体阻滞剂)14.9%、31.2%和62.6%、硝酸盐类42.5%、48.2%和56.9%、非洋地黄类正性肌力药物25.7%、28.9%和17.7%、钙离子拮抗剂17.5%、18.3%和22.3%。不使用β-blocker的主要原因是窦性心动过缓。不使用ACEI/ARB的主要原因是低血压。未考虑使用β-blocker占不用原因的30.8%,未考虑使用ACEI/ARB占不用原因的31.5%。结论提示自心力衰竭治疗指南公布以来,绵阳市心力衰竭患者规范化药物治疗水平有了明显提高。
[Objective] To make a detailed survey of the status for medicine using of chronic heart failure （CHF） in Mianyang City. [Methods] By utilizing the medical history database of the patients of three municipal hospitals in the year of 1998, 2001 and 2005, the status of drug using for the treatment of CHF patients has been analyzed. [Results] There were total of 2038 patients with CHF in the year of 1998, 2001 and 2005. The status of used medication is described. For diuretics, the using rate was 63.7, 68.1 and 77.6% in 1998, 2001 and 2005, respectively; for digitalis, the data was 40.2%, 42.4% and 68.6%; for angiotensin-converting enzyme inhibitors/angiotensin Ⅱ receptor blocker （ACEI/ARB） 18.2%, 30.3%, 62.4%; for β-blocker 14.9%, 31.2%, 62.6%; for nitrate, the data was 42.5%, 48.2%, 56.9%; for non-digitalis positive inotropic drugs 25.7%, 28.9%, 17.7% and 17.5%, 18.3%, 22.3% for calcium channel blocker （CCB）. The patients with sinus bradycardia excluded the using of β-blocker and the patients with hypotensive excluded ACEI/ARB. Those patients who did not consider using β-blocker amounts about 30.8% of those who did not using β-blocker and the corresponding situation for ACEI/ARB is 31.5%. [Conclusion] The criterion situation for using medication for CHF in Mianyang has been improved since the therapy guild for CHF was issued.
出处
《中国现代医学杂志》
CAS
CSCD
北大核心
2007年第1期76-79,共4页
China Journal of Modern Medicine
关键词
心力衰竭
慢性
药物治疗
heart
failure
chronic
drug therapy
