摘要
目的提高药物难治性癫痫的致痫灶精确定位和外科治疗水平。方法对26例颞叶癫痫患者应用长程视频脑电进行术前监测定位和皮层电极、深部电极进行术中定位;采用显微外科技术进行病灶+颞叶切除或颞叶+海马杏仁核切除。结果26例患者根据脑电图,18例患者根据MRI检查定位了致痫灶。术后无病死和严重并发症,服用抗癫痫药物减少;随访6～18个月,1级16例,2级6例,3级4例。结论长程视频脑电图和MRI检查是定位癫痫灶可靠的检查方法。应用显微外科技术可减少并发症,取得较好的治疗效果。
Objective To improve localization and effective surgical treatment of refractory epilepsy. Methods 26 patients with temporal lobe epilepsy were located by the detection of EEG （long-term video EEG,intracranial EEG）. Different resections were performed by microsurgical techniques,temporal lobectomy in 6 cases,temporal lobectomy plus hippocampectomy in 20 cases. Results Among the total 26 patients,epileptogenic zones were localized by long-term video-EEG recording and MRI in 18 patlents.Follow-up for 6 to 18 months was available for all patients.No severe complication and death occurred after operation; and administration of anti-epilepsy drugs was reduced.ln 16 patients seizure were free,seizure frequency reduced more than 75% in 6 patients and reduced more than 50% in 4 patients.Conclusion Long term video-EEG and MRI are reliable methods for localizing cpileptogenic zone. Good effects could be obtained by microsurgical treatment for refractory epilepsy.
出处
《实用医药杂志》
2007年第1期28-29,共2页
Practical Journal of Medicine & Pharmacy
关键词
颞叶癫痫
脑电图
前颞叶切除术
Temporal lobe epilepsy EEG Anterior temporal lobeetomy
