摘要
目的：观察内镜下微创手术治疗食管黏膜下肿瘤的疗效及安全性，并探讨食管黏膜下肿瘤的临床病理特征。方法：经胃镜诊断为食管黏膜下肿瘤患者33例，男23例，女10例，年龄34～85岁，平均51．2岁，分别采用内镜下黏膜切除术（EMR）或针状刀剥离术切除肿瘤，切除标本行常规病理及免疫组化检查。术后内镜随访。结果：33例患者均为完全切除，肿瘤直径为0．5～2．5cm，病理组织学显示食管平滑肌瘤25例、间质瘤3例、脂肪瘤和血管瘤各2例、黏膜下囊肿1例。5例发生术后即刻创面渗血，经局部喷洒止血药或钛夹止血，术后6例有轻度胸骨后疼痛，未发生其他与手术相关的并发症。随访2～30个月，所有患者均无复发。结论：对于〈2cm的腔内生长型食管黏膜下肿瘤，内镜微创手术是安全有效的治疗方法。
Objective：To evaluate the effectiveness of endoscopic minimally invasive treatment for submucosal tumors of the esophagus. Methods ： Included in the study were 33 patients with esophageal submucosal tumors, male 23 and female 10 cases, aged 34 -85 years（average 51.2）. The lesions were removed by means of endoscopic mucosal resection （ EMR）, or stripping-resection method, i. e. , first stripped by a needle knife and followed by ＂injection and cut＂. Results：All the lesions were resected completely by endoscopic minimally invasive methods. Of 33 lesions, 15 cases were undertook EMR, and 18 cases were treated by stripping-resection method. Except 5 cases of treatable bleeding, and 6 cases of post-operative substernal pain, no other complications were found. Pathological exam and immunohistochemical study showed that 25 cases were esophageal leiomyoma, 3 cases of stromal tumor, 2 cases of lipoma, 2 cases of haemangioma and 1 case of submucoal cyst. No recurrence was found during the followup of 2 -30 months. Conclusion：Endoscopic minimally invasive therapy is effective and safe for the treatment of esophageal submucosal tumors.
出处
《医学研究生学报》
CAS
2007年第1期36-38,共3页
Journal of Medical Postgraduates
基金
人事部留学回国人员科研活动择优资助课题(南人字2004第83号)
关键词
食管肿瘤
黏膜下
治疗
微创手术
内镜下黏膜切除术
免疫组织化学
Esophageal tumor, submucoal
Minimally invasive therapy
Endoscopic mucosal resection
Immunohistochemistry
