摘要
目的观察卡托普利与环磷腺苷葡胺(MCA)联用治疗慢性充血性心力衰竭(CHF)疗效。方法通过52例此类患者,给予环磷腺苷葡胺120 mg加入5%葡萄糖注射液250 mg静脉点滴,每日1次,共14 d,卡托普利,从小剂量6.25 mg 3次/d开始,1周后逐渐加量至12.5 mg,3次/d。结果心功能Ⅲ级,有效率为93.3%,心功能Ⅳ级有效率91.0%,两组左室射血分数(EF)显著增高,左室舒张末期内径(LVEDD)均明显减小。经统计学处理P<0.05,作用显著。结论卡托普利与环磷腺苷葡胺联用治疗慢性充血性心力衰竭疗效显著。
Objective To investigate the therapeutic effect of captopril and MCA for CHF. Methods 52 CHF patients were enrolled. MCA 120 mg in 5% glucose 250 ml was infused once daily for 14 days; captopril dosage increased from 6.25mg tid to 12.5mg tid in a week. Results The response rate was 93.3% for patients with cardiac function Ⅲ; The response rate was 91.0% for patients with cardiac function Ⅳ. The LVEF increased significantly（ P〈0.05） and LVEDD decreased significantly（ P〈0.05） in both groups. Conclusion Captopril and MCA have proved efficacy in congestive heart failure.
出处
《临床和实验医学杂志》
2007年第1期59-59,61,共2页
Journal of Clinical and Experimental Medicine
