摘要
目的探讨慢性支气管炎急性加重期血清嗜酸细胞阳离子蛋白(ECP)与糖皮质激素疗效关系。方法采用荧光酶标法Pharmacia CAP检测系统测定慢性支气管炎急性加重期血清ECP及1 s用力呼气容积(FEV1)。结果血清ECP值慢性喘息型支气管炎显著高于慢性单纯型支气管炎,治疗后ECP显著下降,肺功能显著改善。结论血清ECP可作为临床使用糖皮质激素的指征,指导临床使用糖皮质激素。
Objective It is to study the relationship between eosinophil cationic protein （ECP） and the effect of corticosteroid in chronic bronchitises with acute attack. Methods Serum ECP was measured with pharmacia CAP system and FEVt was examined with pheumometer in patients with chronic bronchitises in acute stage. Results The content of serum ECP was obviously higher in patients with gasping type of chronic bronchitises than that with simple type. The content of ECP was significantly decreased and the lung function was obviously improved after treatment. Conclusion Serum ECP can be used as indication of clinical application of glucocorticoid to guide for the treatment for chronic bronchitises with attack.
出处
《现代中西医结合杂志》
CAS
2007年第4期444-445,共2页
Modern Journal of Integrated Traditional Chinese and Western Medicine
关键词
ECP
糖皮质激素
慢性支气管炎
eosinophil cationic protein
glucocorticoid
chronic bronchitises
