摘要
目的：探讨HBV感染者唾液中HBV—M与HBV—DNA的相关性，唾液是否是乙型肝炎传染的重要途径之一。方法：采用酶法对2005-2006年HBV感染患者，分别进行血清学和唾液的收集与检测，对HBV感染的患者血清型分成常见的10种类型，同时对所选乙肝感染的患者的唾液进行荧光定量PCR定量测定HBV—DNA。结果：急性感染组和慢性感染与携带者组HBV—DNA阳性率比较，差异有显著性（P〈0．05）。结论：乙肝患者唾液中含有HBV—DNA，高病毒血症的患者唾液中含有大量HBV—DNA，唾液具有潜在传染性。可以解释，通过水平传染可能就是20％HBV感染者的感染源。唾液是乙肝一个重要的传播途径，要引起重视。
Objective ：To discuss the correlation of HBV-M and the HBV-DNA in saliva of patients infected HBV, and discover the saliva whether is an important way of hepatitis B infection or not. Method ：The aliva and serum of patients infected HBV in 2005-2006 year were collected and examinated ban enzymelaw ,and at the same time,the aliva of patients infected HBV was carried on fluorescence quota PCR quantitative determination HBV-DNA. Results：There was a significance difference to compare the positive rate of HBV-DNA in acute infecting group,chronic infecting group and carried person （P〈0. 05）. Conclusion：The saliva of patients with hepatitis B includes HBV-DNA,in the saliva of pa- tients with high sick viremia includes massive HBV-DNA,and the saliva has the latent infection. The saliva is a hepatitis B important dissemination way,must bring to the attention.
出处
《中国误诊学杂志》
CAS
2007年第2期209-211,共3页
Chinese Journal of Misdiagnostics
