摘要
目的:评价益气平喘颗粒治疗气虚寒哮证急性支气管哮喘的安全性及有效性。方法:采用随机阳性药平行对照试验设计,共纳入80例受试者,按3∶1的比例随机分为试验组(益气平喘颗粒)60例和对照组(如意定喘丸)20例,疗程共7d。结果:治疗组与对照组的中医证候、临床症状和肺功能比较差异均无统计学意义(P>0.05)。治疗组治疗后1秒钟用力呼气容积增大(P<0.05),对照组治疗后呼气峰流速加快(P<0.05)。两组在用药期间均未发生不良反应。结论:益气平喘颗粒治疗气虚寒哮证支气管哮喘安全有效。
Objective： To evaluate the safety and efficacy of Yiqi Pingchuan Granule in treating acute attack of asthma due to qi deficiency and cold syndrome.
Methods： A randomized controlled trial was conducted. A total of 80 patients with an acute attack of asthma were included. They were allocated into two groups randomly in a ratio of three to one. Sixty patients in the treatment group received Yiqi Pingchuan Granule and 20 patients in the control group received Ruyi Dingchuan Pill. Patients in both groups were treated for 7 days.
Results. There were no significant differences in traditional Chinese medicine syndrome, clinical symptoms and lung function between the two groups （P〉0.05）. After treatment, the forced expiratory volume in 1 second was increased in the treatment group （P〈0.05）, and the peak expiratory flow was accelerated in the control group （P〈0.05）. No significant side effects were noted in both groups.
Conclusion： Yiqi Pingchuan Granule is safe and effective in treating acute attack of asthma due to qi deficiency and cold syndrome.
出处
《中西医结合学报》
CAS
2007年第1期23-27,共5页
Journal of Chinese Integrative Medicine
关键词
中草药制剂
随机对照试验
支气管痉挛
哮喘
herbal preparations
randomized controlled trials
bronchial spasm
asthma
