摘要
以坐骨神经损伤的豚鼠为动物模型，采用免疫细胞化学方法，研究脊髓前角运动细胞神经生长因子（Ｎｅｒｖｅｇｒｏｗｔｈｆａｃｔｏｒ，ＮＧＦ）的变化。结果表明，ＮＧＦ－ｉｒ免疫阳性产物见于前角运动核背外侧群（ＤＬ）、腹外侧群（ＶＬ）、中间群（Ｃ）、后背外侧群（ＲＤＬ），损伤侧ＮＧＦ免疫反应染色明显深于对照侧，第４ｄ染色达到高峰。提示ＮＧＦ在坐骨神经损伤后，可能具有营养。
The changes of nerve growth factor(NGF) in motor neuron of anterior horn of spinal cord in guinea pigs with nerve injury were studied with immunohistochemical technique. The results showed that NGF-immunoreaction positive stained products were found in dorsolateral ,ventrolateral ,central and rear dorsolateral parts. NGF immunoreaction staining was darker in injured side than in the control side. The staining was darkest on the 4th day. It is indicated that when sciatic nerve was injured ,NGF may nourish the injured nerve and promote its regeneration.
出处
《武警医学》
CAS
1996年第6期320-322,共3页
Medical Journal of the Chinese People's Armed Police Force
关键词
坐骨神经损伤
脊髓
运动神经元
神经生长因子
Sciatic nerve Motor neuron of anteriohorn of spinal cord Nerve growth factor Guinea pig
