摘要
神经营养因子家族是一类重要的神经营养因子,其受体包括Trk和p75受体,这两类受体通过引发不同的信号转导途径发挥不同的,有时甚至是相反的生物学效应。两类受体之间又存在复杂的相互作用,共同调节神经元的发生、存活、损伤、修复和死亡。
Neurotrophic factor family is a category of important neurotrophic factors, its receptors include Trk and p75 receptors. Both of them exert different biological effects by initiating different signal transduction pathmays, sometimes even adverse biological effects, There are complicated interactions between the two kinds of receptors, They jointly regulate neuron genesis, survival, injury, repair, death.
出处
《国际脑血管病杂志》
2006年第11期870-873,共4页
International Journal of Cerebrovascular Diseases
基金
国家自然科学基金(No30260029)
关键词
神经营养因子
受体
信号转导
neurotrophic factor
receptor
signal transduction
