摘要
目的 通过对105株肺炎克雷伯菌的分布特征及耐药性分析，指导临床合理用药。方法 细菌鉴定采用API系统，药敏采用琼脂扩散法，结果 判定按NCCLS标准执行，数据统计按世界卫生组织细菌耐药性监测组软件WHONET4系统处理。结果标本来源以病人的痰液，尿液，伤口分泌物为主，产ESBLs检出率为36％，科室分布以老年病房最多，耐药性对碳青霉烯类抗生素高度敏感，对阿米卡星敏感率较高，对青霉素类敏感率很低（0％-18％）。结论 肺炎克雷伯菌对临床常用抗生素的耐药率较高，所以合理选用抗生素很重要。
Objective To investigate the antimicrobial resistance and clinical distribution of nosocomial infection pathogens and to provide the reference for the clinical treatment and infection control in hospital. Methods The bacteria assay adopted API system, the drug resistant were taken by agar diffuse method, the test of ESBLS klebsiella were taken by K-B method, according to NCCLWS and using WHO NET4 software for data statistics. Results Most strains were isolated from sputum, urine and wound. The test rate of was 36%; Departments of geriatrics were the most likely place of ESBLs klebsiella pneumoniae; the strains of ESBLs klebsiella pneumoniae had low resistance against Carbapenem antibiotics .The sensitivity rate to amikacin was higher （86%）, to Penicillin, AmpiciUin, piperacillin was lower （0%-18%）. Conclusions ESBLs klebsiella pneumoniae are seriously resistant, It＇s very important to select antibiotics correctly for infection according to the results of susceptibility test.
出处
《世界感染杂志》
2006年第6期529-531,共3页
World Journal of Infection
关键词
肺炎克雷伯菌
分布特征
耐药性
klebsiella pneumoniae
clinical distribution
resistance
